Medyra
Hormones

Reviewed: 13. Juli 2026

E2 Estradiol

Unit: pg/ml

Quick Explanation

Estradiol is the most important female sex hormone and fluctuates strongly during the cycle, pregnancy, and menopause. Low values can indicate menopause or an ovarian dysfunction; the reference range depends heavily on cycle phase and age.

📊 Reference Values

Normal (cycle-dependent)
20 – 400 pg/ml

ℹ️ Reference ranges may vary slightly between laboratories. Always compare your value with the reference range from your own lab report.

🔍 Possible Causes

Value too high — possible causes

  • ·Certain cycle phases (e.g. ovulation)
  • ·Pregnancy
  • ·Estrogen-producing tumors (rare)

Value too low — possible causes

  • ·Menopause
  • ·Ovarian dysfunction
  • ·Significant weight loss or competitive sports

This list shows possible causes — not a diagnosis. Only your doctor can correctly interpret your result.

🩺 Questions for Your Doctor

  • Does my estradiol value match my current cycle phase or life stage?
  • Should other hormone values be measured?

Have a complete lab report?

Medyra explains your entire lab report in plain language and prepares questions for your doctor appointment — free, in your language, in under 60 seconds.

Start for free →
⚠️

Medical Disclaimer

The content on this page is for general information only and does not replace professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist for health-related questions. Lab values should always be assessed in the context of your personal medical history.

Estradiol explained | Medyra | Medyra AI